According to our projections, the best bet against the spread among Week 14’s 67 FBS matchups is Florida (+11.5) — for more suggestions, including parlay possibilities, scroll down.

Look for insights and computer predictions for that matchup and more below.

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College Football Computer Picks – Best Spread Bets

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Pick: Florida +11.5 vs. Florida State

• Matchup: Florida Gators at Florida State Seminoles
• Projected Winner & Margin: Florida by 17 points
• Time: 1:00 PM ET
• Date: Nov. 30
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Ohio State -10 vs. Michigan

• Matchup: Michigan Wolverines at Ohio State Buckeyes
• Projected Winner & Margin: Ohio State by 23.2 points
• Time: 12:00 PM ET
• Date: Nov. 30
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: North Carolina +3.5 vs. North Carolina State

• Matchup: North Carolina State Wolfpack at North Carolina Tar Heels
• Projected Winner & Margin: North Carolina by 8.6 points
• Time: 3:30 PM ET
• Date: Nov. 30
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Notre Dame -3.5 vs. USC

• Matchup: Notre Dame Fighting Irish at USC Trojans
• Projected Winner & Margin: Notre Dame by 13 points
• Time: 3:30 PM ET
• Date: Nov. 30
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo

Pick: Louisville +1 vs. Kentucky

• Matchup: Louisville Cardinals at Kentucky Wildcats
• Projected Winner & Margin: Louisville by 8.4 points
• Time: 12:00 PM ET
• Date: Nov. 30
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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College Football Computer Picks – Best Total Bets

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