Best Bets for NCAA Basketball Picks Against the Spread for Saturday, December 21

Published 6:23 pm Friday, December 20, 2024

ATS Pick: North Florida +23.5 vs. Florida

• Matchup: North Florida Ospreys at Florida Gators
• Time: 12:00 PM ET
• Date: December 21
• Computer Projection: Florida by 16.4 points (Bet now on BetMGM)
• Spread: Florida (-23.5)
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Lamar +21.5 vs. Texas Tech

• Matchup: Lamar Cardinals at Texas Tech Red Raiders
• Time: 1:00 PM ET
• Date: December 21
• Computer Projection: Texas Tech by 15.3 points (Bet now on BetMGM)
• Spread: Texas Tech (-21.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Arizona State -9.5 vs. UMass

• Matchup: Arizona State Sun Devils vs. UMass Minutemen
• Time: 4:00 PM ET
• Date: December 21
• Computer Projection: Arizona State by 15.1 points (Bet now on BetMGM)
• Spread: Arizona State (-9.5)
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: N.C. A&T +29.5 vs. Arkansas

• Matchup: North Carolina A&T Aggies at Arkansas Razorbacks
• Time: 2:30 PM ET
• Date: December 21
• Computer Projection: Arkansas by 24.3 points (Bet now on BetMGM)
• Spread: Arkansas (-29.5)
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Texas A&M-CC +27.5 vs. Houston

• Matchup: Texas A&M-CC Islanders at Houston Cougars
• Time: 2:00 PM ET
• Date: December 21
• Computer Projection: Houston by 22.3 points (Bet now on BetMGM)
• Spread: Houston (-27.5)
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: Nevada -10.5 vs. Colorado State

• Matchup: Colorado State Rams at Nevada Wolf Pack
• Time: 5:00 PM ET
• Date: December 21
• Computer Projection: Nevada by 15.1 points (Bet now on BetMGM)
• Spread: Nevada (-10.5)
• TV Channel: MW Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: DePaul +7.5 vs. Northwestern

• Matchup: DePaul Blue Demons at Northwestern Wildcats
• Time: 4:00 PM ET
• Date: December 21
• Computer Projection: Northwestern by 3 points (Bet now on BetMGM)
• Spread: Northwestern (-7.5)
• TV Channel: BTN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Central Michigan +24.5 vs. Arizona

• Matchup: Central Michigan Chippewas at Arizona Wildcats
• Time: 4:00 PM ET
• Date: December 21
• Computer Projection: Arizona by 20.4 points (Bet now on BetMGM)
• Spread: Arizona (-24.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Queens +25.5 vs. Ole Miss

• Matchup: Queens Royals at Ole Miss Rebels
• Time: 5:00 PM ET
• Date: December 21
• Computer Projection: Ole Miss by 21.4 points (Bet now on BetMGM)
• Spread: Ole Miss (-25.5)
• TV Channel: SEC Network+

ATS Pick: Butler +5.5 vs. UConn

• Matchup: UConn Huskies at Butler Bulldogs
• Time: 12:00 PM ET
• Date: December 21
• Computer Projection: UConn by 1.7 points (Bet now on BetMGM)
• Spread: UConn (-5.5)
• TV Channel: Peacock